15-PGDH Inhibitor

Code: 100073-10MG D2-231

General description

A cell-permeable, thiazolidinedione derivative that acts as a 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor (IC50 = 25 nM). It is s...


read more

Your Price
€202.90 10MG
€249.57 inc. VAT

General description

A cell-permeable, thiazolidinedione derivative that acts as a 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor (IC50 = 25 nM). It is shown to increase PGE2 levels in IL-1β-stimulated A549 cells, dose-dependently, in the range of 0–20 µM, and elicits cochlear blood flow (CBF) increase by 15% and 55% when applied intravenously to 250 g guinea pigs at 10 µg and 20 µg respectively.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Wu, Y., et al. 2011. J. Med. Chem.54, 5260.

Packaging

Packaged under inert gas

10 mg in Glass bottle

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Standard Handling (A)

assay≥99% (HPLC)
coloryellow
formsolid
manufacturer/tradenameCalbiochem®
Quality Level100
shipped inambient
SMILES stringO=C(NC/1=O)SC1=C/C2=CC=C(OCCC3CCCCC3)C(OC)=C2
solubilityDMSO: 100 mg/mL, clear, pale yellow
storage conditionprotect from light, OK to freeze
storage temp.2-8°C
Cas Number1239610-60-6
This product has met the following criteria to qualify for the following awards:



PROCEED TO CHECKOUT

HAVE AN ACCOUNT? LOGIN


GUEST CHECKOUT

Proceed as a guest. You will have the option to register to access exclusive pricing and stock availability features after checkout.